Nutrigenomics & Nutrigenetics
I have been fascinated with genetics ever since I learned that our current genetic expression is a result of our current environment and our genetics are not set in stone, as once believed.
Thats powerful, we can activate and deactivate our genes, either making us stronger, increasing health and longevity or making us fat, weak, and compromised, ending in chronic illness’s such as cancer, heart disease and diabetes.
We all have our individual variations of the same genes, these are called alleles. The gene for blue eyes is an allele. As is the gene for brown eyes. A lot of genes like the ones for eye colour, are written in permanent marker before we are born and there is nothing we can do to change them, yet.
Epigenetic’s and SNP’s
Other genes however, have an epigenetic expression. Epi meaning above, and then genetics so, above your genetics. These are the genes that are written in pencil and we can influence there expression with our nutrition, lifestyle and environment.
When we are conceived, we inherit one allele or copy of each gene from our parents, this creates 3 possible expression of that gene.
The first, is the expected variation of that gene, referred to as the Wild Type.
Then, there are two potential Single Nucleotide Polymorphisms or SNP’s, referred to as ‘SNIPS’. These are the variations that impact our biology and physiology at the most cellular level.
- Wild Type – This is the expected expression, meaning the gene is the expected variation with no negative impact.
- Heterozygote – Two different copies of that gene. This could have a slight negative or slight positive impact.
- Homozygote – Both parents gave you the same copy of that gene. This could be really bad, or really good.
So, if you get the same SNP from both parents, you could be expressing the worst variation of that gene, which may be contributing to weight gain, high blood pressure, elevated LDL, depression, chronic fatigue, brain fog, poor physical performance and, the list goes on.
You see, genes activate enzymes in the body and enzymes go and do specific jobs. They range from enzymes to help your bodies detoxification pathways clear heavy metals and toxic mould, to enzymes that convert essential vitamins into their required active compounds. Such as the MTHFR gene that is responsible for converting the inactive vitamin B9 folic acid into the bioavailable active B9 methyl folate.
Other genes effect the way you metabolise fats, caffeine, salt and sugar. Knowing this stuff gives you total control over your nutrition and removes the guess work!
If you are getting good quality sleep, eating a nutrient dense whole-food diet, get outside and move a lot, have a good mindset and have your environment dialled in, chances are you will be fit, strong and robust with the best expression of your genes activated.
Even if you do have all of that dialled in, your genes my still need some attention. Without testing, we simply do not know. I know from my own experience, I had all of the key areas dialled in but my own DNA testing, highlighted some areas I needed to address.
The main problem for most people though is, in our modern society, we don’t pay attention to our sleep, we eat man made fast and easy food, we are sedentary, stressed out and living in a world of of artificial lighting and increased environmental toxins.
By testing our own DNA and getting reports on our personal SNP’s, we can take an individualised approach to our nutrition and lifestyle.
This is a far better way to optimise our health, as apposed to following the current ‘one size fits all’ approach to healthcare and nutrition.
How does the testing work?
A test kit is sent to your home or work, you take a few swabs of saliva and sweat then return it to the lab in the prepaid postage bag provided.
The tests I currently use are from DNA LIFE and are split into four categories of testing and reporting.
You can select any single test or, any combination of tests. You can also view sample reports for each test.
One of the first products of its kind in the world, DNA Diet is designed to assist the healthcare practitioner in the design of a personalised weight management plan based on individual genetic differences.
DNA Diet also provides additional insight into how each individual reacts to carbohydrates, saturated fats and intensity of exercise, allowing further personalization of your eating plan to suit your needs.
DNA Diet tests a number of well-researched gene variations that impact metabolism, absorption and storage of fats and carbohydrates, as well as eating behaviour. We have analysed these SNPs to understand how an individual’s genetic profile will impact their response to what we believe to be the three most effective healthy eating plans. i.e. Low fat, Mediterranean, and Low Carbohydrate. Research suggests that individuals do respond differently to different food combinations and no ONE way of eating is right for everyone.
DNA Diet Sample Report CLICK HERE
The DNA Health test is designed to optimise wellbeing and health by personalising lifestyle and diet choices and, where necessary, using supplements tailored to offset any particular nutritional deficit based on specific gene variants. The DNA Health approach assists the healthcare practitioner in establishing the optimal nutrition necessary for good health, longevity and disease risk mitigation.
DNA Health tests for 36 gene variants involved in the following biological processes that have been linked to risk for diseases of lifestyle:
- Cholesterol metabolism
- Bone Health & risk for osteoporosis
- Methylation and risk for cancer
- Inflammation and oxidative stress
- Insulin Sensitivity and risk for diabetes
- Food Responsiveness, including Lactose intolerance, Caffeine processing, Salt sensitivity and blood pressure & Iron overload disorders
DNA Health Sample Report CLICK HERE
DNA Sport examines various biological areas that impact training responsiveness and sporting performance. These include soft tissue remodeling, inflammation, blood flow and respiration, energy production and fuel metabolism.
Athletic success results firstly from personalising a training strategy that optimises your genetic potential, and secondly choosing the right lifestyle, nutrition and environmental interactions to optimally express your inherited genes.
DNA Sport reports on the following areas:
- structural integrity of soft tissues
- inflammation & oxidative stress
- blood flow & respiration
- energy during exercise
- fuel during exercise
- caffeine metabolism
- muscle and bone composition
- aerobic capacity
- power/strength potential
Knowledge of variations in genes involved in these biological areas can be used to personalise a training program in order to gain as much as possible from sessions by exploiting potential advantages, as well as to identify weaknesses that need to be worked on. This insight can also be used to make appropriate training and nutrition choices in an attempt to prevent injury as well as optimise recovery in order to perform at one’s best.
DNA Sport Sample Report CLICK HERE
80% of breast cancer occurs in women with no family history. Oestrogen gene testing may help you lessen your risk. Research has shown that an increased lifetime exposure to oestrogen is a strong risk factor in the development of breast cancer. DNA Oestrogen tests for gene variants that have been shown to have an impact on how oestrogen is processed in your body and if the processing of oestrogen and related compounds is efficient and healthy.
Oestrogen affects the function of a number of target tissues. Guiding the personalisation of diet, hormone and nutritional supplement recommendations, based on the insight gained from the DNA Oestrogen test, is of benefit to men and women who suffer from numerous oestrogen-dominant conditions.
DNA Oestrogen reports on the following areas:
- Variations in key genes involved in metabolizing oestrogen and related compounds
- Intervention strategies for carriers of high-risk genetic variations
- Personal risk factors associated with HRT, Oral contraceptives, bio-identical supplementation and in vitro fertilisation
DNA Oestrogen Sample Report CLICK HERE
How much does it cost?
Here are the prices for various combinations of the four tests available.
All Four Reports – Ideal for Females.
Health, Diet, Sport, Oestrogen £399
Three Reports – Ideal for Men
Health, Diet, Sport £349
Diet, Sport £299
Diet, Oestrogen £299
Diet, Health £299
Health, Sport £299
What happens after you get the report’s back?
I am a certified DNA Life Practitioner and Functional Nutritionist and will be more than happy to guide you through your reports. This is not essential as the reports are very clear and easy to understand, but sometimes it’s nice to have an expert go over them with you and make specific recommendations. I can also order further lab testing, should you require it.
How to order DNA tests or get more info
If you would like to order any of the tests or would like more information about DNA Testing, please click the link below and complete the form to arrange for a test kit to be posted to you, or a you can select to receive a phone call from myself to discuss it further.